| | | | Welcome to the second edition of the UniQuest newsletter for 2025 - a collaborative initiative of the Deputy Vice-Chancellor (Research & Innovation) and UniQuest, The University of Queensland's commercialisation company.
A team from UniQuest joined others from across UQ to attend the BIO2025 International Convention at Boston in June, showcasing the brilliant technology from UQ researchers that is available for partnering and licensing on the world stage. Our team have condensed their key insights from the event. Check it out if you're a researcher in the life sciences space who is considering commercialising your research.
This quarter we celebrated vital grant funding that will advance a potential new therapy for prostate cancer, in a joint project from the lab of Professor Greg Monteith and our drug discovery arm, QEDDI.
There's still time to register to attend UniQuest's annual Research Commercialisation Workshop, to be held at the end of July over two days. If you haven't yet had the chance to attend, make this your year and follow the link below to sign up.
We trust you enjoy this edition. | | | Professor Sue Harrison Deputy Vice-Chancellor (Research & Innovation) | | |
Dr Dean Moss CEO, UniQuest Pty Ltd | | |
Newsletter in
Brief - BIO2025: Evolving trends in therapeutic development and pharma interests.
- Therapy hope: Advanced prostate cancer drug a step closer to the clinic.
- Hot takes: AEA results, ovarian cancer test, innovation champion, Haon Life Sciences invests in UQ tech, Knowledge Exchange UK, a quantum pitch.
- AlphaFold3: The case for UQ researchers to switch to MIT's Boltz.
- Dalton Horizon: UQ researcher awarded Royal Society of Chemistry Prize.
- Who are we: Meet UniQuest's Dr Yvonne Booth.
| | | | | The UniQuest team who attended BIO2025 in Boston (left to right): Senior Director, Commercialisation - Life Sciences, David Markwell; Director of Business Development - QEDDI, Laura Kearney; Senior Director, Commercialisation - Life Sciences, Dr Tamsin Terry; Head of Life Sciences Dr Craig Belcher; and Associate, Commercialisation - Life Sciences, Dr Adam Stephenson. Not pictured: Director, Commercialisation - Life Sciences, Dr
Idalia Ridley and Head of Strategic Partnerships, Dr Andrew Harvey, | | BIO2025: Therapeutic development trends & pharma interests The BIO International Convention held at Boston in June offered a compelling glimpse into the future of therapeutic development.
The UniQuest team held more than 95 meetings with companies in the life science space, seeking feedback and interest in specific projects in the UniQuest pipeline from UQ researchers, as well as gaining insights on specific industry needs.
Click here for their key takeaways across antibody innovation, translational pain models, peptide therapeutics, obesity and ageing biology, evolving biotech partnerships, women's health and AI-driven drug discovery. | | | | | | |
(L to R): QEDDI's Drug Discovery Team Leader Dr Kim Beaumont, Head of QEDDI Dr Brian Dymock, Medicinal Chemistry Team Leader Dr Rebecca Pouwer and Senior Drug Discovery Scientist Mei-Chun Yeh in the lab. | |
Advanced prostate cancer drug a step closer to the clinic A $1.25 million investment is driving the development of a new treatment for advanced and therapy-resistant prostate cancer at The University of Queensland.
Based on research by Professor Greg Monteith from UQ's School of Pharmacy and Pharmaceutical Sciences, QED-203 is being developed by the Queensland Emory Drug Discovery
Initiative (QEDDI), UniQuest's small molecule drug discovery group.
The vital injection is from US-based global drug accelerator Critical Path Institute's Translational Therapeutics Accelerator (TRxA).
Watch the video here.
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| | | | Hot takes - Irish
investment: Congratulations to UQ Frazer Institute's Professor Kiarash Khosrotehrani and Dr Jatin Patel (now ex-UQ) whose stem cell technology was licensed to Irish company Haon Life Science with an AU$18m investment to develop a vital treatment for neonatal brain injury.
- Quantum pitch: Congratulations to Senior Director, Commercialisation - Physical Sciences, Peter Baines, who pitched the technology behind UQ-spinout VeriQuantix (from researchers at UQ's School of Mathematics and Physics) at the Australian Cyber Exchange Conference ACE25 Showcase startup pitch competition and won first place (out of 27).
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The AlphaFold 3 licensing maze: Consider MIT's Boltz instead AlphaFold 3 is a modelling tool for predicting biomedical structures that made headlines for its expanded capabilities and ability to model proteins, nucleic acids, small molecules and more.
But for UQ researchers hoping to translate discoveries into commercial applications, there's a catch. AlphaFold 3 is not truly open-source, and its license
explicitly restricts use to non-commercial activities.
UQ researchers should consider using alternatives for projects that may have commercial potential. Alternatives to consider include AlphaFold 2, which was released with a more permissive licence, or Massachusetts's Institute of Technology's Boltz-2.
Released under the permissive MIT license, Boltz-1 and 2 are fully open-source and commercially usable.
Boltz-2 improves on the successes of Boltz-1 as an AlphaFold 3 alternative. It is able to predict protein-ligand binding affinities at accuracies approaching the expensive physics-based free energy perturbation methods and supports complex biomolecular modeling tasks.
Learn more here. | | | | | UQ researcher's hybrid glass innovation wins Dalton Horizon | | | | | | Senior Associate, Commercialisation - Life Sciences Yvonne grew up on the west coast of Scotland but fell in love with Australia on a short family holiday to Perth when she was just 16.
She studied Medicinal Chemistry at the University of Sheffield and did an exchange year abroad at UQ, obtaining an International Postgraduate Research Scholarship that allowed her to return to UQ to complete a PhD in Organic Chemistry.
Yvonne
returned to the UK to apply her skills and training in a pharmaceutical industry-based role and spent several years as a synthetic chemist at Peakdale Molecular Ltd, providing contract chemistry services.
"At this point I wanted to move away from the lab bench but still have a role in science being used in an applied, commercial way," she said. "So, the logical step was to pivot to the world of patents."
Yvonne spent two years as a trainee patent attorney with Marks and Clerk LLP, training under qualified UK and European patent attorneys and gaining practical experience of patent requirements, including drafting and prosecution.
Her passion for Australia never dimmed, and Yvonne returned to Brisbane in 2015 to commence a role at UniQuest.
She said it was a great opportunity to use her scientific and IP background and extend into some of the more commercial
aspects of business development and licensing.
"I've worked on a range of life sciences technologies for human health with a focus on therapeutics and particularly small molecules, peptides and more recently, encompassing radiopharmaceuticals," Yvonne said of her time in the Life Sciences team.
"It's incredibly gratifying trying to help scientific research transition from an academic lab and out into a commercial environment where it can potentially benefit patients."
Contact Yvonne. |
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UniQuest acknowledges the Traditional Owners and their custodianship of the lands on which The University of Queensland and UniQuest are situated. We pay our respects to their Ancestors and their descendants, who continue cultural and spiritual connections to Country. We recognise their valuable contributions to Australian and global society. | | |
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