Septic reactions in recipients of bacterially contaminated blood products, particularly platelets, are one of the major sources of transfusion-related mortality. The gold standards for detecting bacteraemia are culture-based methods, however these methods are affected by a high rate of false positive and prolonged time-to-diagnose. Bacterial contaminants represent the largest part of false positive results.

UQ researchers have developed a novel molecular surface architecture to decorate magnetic nanoparticles to capture and tag bacterial contaminants from large sample volumes.

Key features

  • Culture-free nanotechnology
  • Captured 1 CFU/ml in less than 2 hours from blood products
  • Ideal sample preparation for rapid identification technologies (e.g. sequencing, PCR, MALDI).

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