Novel, selective, orally active small molecule antagonists (and agonists) of the human protease-activated receptor 2 (PAR2) have been developed for the potential treatment of inflammatory diseases, metabolic syndrome and cancer.
Key Features
- Novel small molecules
- Orally active
- Effective in models of acute and chronic inflammation, IBD and obesity
- Selective and potent
- Novel target and unique mechanism of action.
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