There is a significant unmet need for therapy of epithelial-associated cancers, which account for 80-90% of all cancers.

Key features

  • UQ researchers have identified a receptor-ligand pair that plays a key role in dysfunctional local presentation of antigen to tumour resident T cells in hyperplasic epithelium
  • Overcoming deficits in antigen presentation within the local tumour environment has potential to significantly enhance T cell mediated anti-tumour responses.

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