Researchers at The University of Queensland have developed a potent and selective peptide inhibitor (Hi1a) of acid-sensing ion channel 1a (ASIC1a), a therapeutic target in acute cardiac myoprotection and acute stroke neuroprotection.

Key Features

  • Potent (picomolar activity) and selective inhibitor of acid sensing ion channel 1a (ASIC1a)
  • First-in-class therapeutic opportunity
  • Efficacy in rodent models of stroke and acute coronary syndrome.
  • Potential for use in other indications

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