Location

Brisbane, Australia

Work Type

Full Time

Closing Date

Friday, 29th July 2017 at 5.00pm

The Company

UniQuest is the main commercialisation company of The University of Queensland (UQ), specialising in the commercialisation of intellectual property, research outcomes and expertise. UniQuest has a 30 year track record and was responsible for the commercialisation of the HPV vaccine Gardasil®, the Triple P Positive Parenting Program, the image correction technology found in two-thirds of the world's MRI machines, and Spinifex Pharmaceuticals, one of Australia's largest biotech acquisitions. With the support of the Queensland State Government and UQ, UniQuest is establishing the Queensland Emory Drug Discovery Initiative (QEDDI), a new dedicated small molecule drug discovery and development capability.  QEDDI aims to develop innovative discoveries into small molecule drug candidates that could progress towards clinical development through industry partnerships or investment in a spin-out company.

As a result, we are currently recruiting for the position of Senior Biologist.

The Role

Reporting to the Director of Biology, the Senior Biologist will perform biology and screening research and development for QEDDI’s small molecule drug discovery programs.

Responsibilities include:

  • Lead a team to plan, execute and analyse studies relating to assay development/optimisation for novel drug targets, including mid-throughput screening activities from target-to-hit to lead optimisation as well as mechanism of action studies.
  • Plan and perform cell based and biochemical assays, design and execute work packages in accordance with project plans
  • Generate robust and complete data sets to make key Go/NoGo decisions on novel drug targets
  • Project leadership to actively drive the ongoing planning, experiments and data analysis, ensuring scientific excellence and industrial rigor to the projects
  • Work diligently and efficiently to meet deadlines in a fast-paced environment
  • Contribute scientific and technical expertise to multiple project teams
  • Coach and mentor the team's technical capability whilst ensuring that they comply with agreed protocols to an industry standard.
  • Manage external contract research organisations in support of this effort.

To be successful in your application, you will need to meet the following criteria:

  • PhD in Immunology, Cell Biology, Neurobiology, or related field with 5 years industry experience in small molecule drug discovery is essential
  • Extensive cellular, biochemical and molecular biology expertise in at least one of the following categories; gene knockdown, enzyme kinetics, protein-protein interactions, cellular efficacy and/or mechanism of action studies
  • Diverse hands-on expertise to include but not limited to biochemical assays, growth or imaging assays, ELISA, Western blotting, si/shRNA techniques, as well as knowledge of CRISPR–Cas9 screening, FACS assays and cellular manipulation such as generation of stable cell lines
  • Proven ability in assay development/optimisation for novel drug targets, including mid-throughput screening activities from target-to-hit to lead optimisation is essential
  • Experience working in projects across different target classes and/or a range of therapeutic areas
  • Previous experience of planning, executing and reporting studies
  • A careful and meticulous nature with strong attention to detail are essential
  • Demonstrated leadership capabilities
  • Strong collaboration skills and excellent ability to work effectively in multidisciplinary teams
  • Effective organisational skills that facilitate planning, multitasking and working within timelines on multiple projects with constantly changing priorities and deadlines

This is a great opportunity to be part of a new initiative that will seek to translate university-based biology into small molecule drug candidates for commercialisation, bringing value to industry, to UQ and to all of Queensland.

Further Information

To apply for the Senior Biologist role, please email your resume and cover letter addressing the selection criteria to jobs@uniquest.com.au. To have a confidential discussion please call Dr Terrie-Anne Cock on +61 (0)0429 415 102.